Research

Education

2013-2018

  • Doctor of Philosophy-Pharmacology
  • Georgetown University
  • Advisor: Stefano Vicini

2006-2010

  • Bachelor of Science-Biochemistry
  • University of Maryland, College Park

Research

2018-2019: Examining the modulation of cortical inhibitory synapses by endocannbinoids.

  • Department of Neuroscience, Yale University
  • Principal Investigator: Michael Higley

2015-2018: Characterizing the morphological and physiological properties of D1 and D2 spiny projection neurons in the nucleus accumbens.

  • Department of Pharmacology and Physiology, Georgetown University
  • Principal Investigator: Stefano Vicini

2014-2018: Determining the role of MMP-1 on motor behavior and interneuronal circuitry in the nucleus accumbens .

  • Department of Pharmacology and Physiology, Georgetown University
  • Principal Investigator: Stefano Vicini

2013-2014: Determining the distinct GABAA receptor subunit composition of synapses between interneurons and spiny projection neurons in the striatum.

  • Department of Pharmacology and Physiology, Georgetown University
  • Principal Investigator: Stefano Vicini

2013: Determining how APOE genotype alters immunoglobulin subtypes.

  • Department of Neuroscience, Georgetown University
  • Principal Investigator: William Rebeck

2010-2013: Characterizing the pharmacological properties of human neuronal nicotinic acetylcholine receptors

  • Department of Pharmacology and Physiology, Georgetown University
  • Principal Investigator: Kenneth Kellar

Publications

  • Nour Al-muhtasib, P. Forcelli, S. Vicini. (2018). Differential electrophysiological properties of D1 and D2 spiny projection neurons in the mouse nucleus accumbens core. Physiological Reports. Full article.
  • Fitch RW, Snider BB, Zhou Q, Foxman BM, Pandya AA, Yakel JL, Olson TT, Al-Muhtasib N, Xiao Y, Welch KD, Panter KE. Absolute configuration and pharmacology of the poison frog alkaloid phantasmidine. Journal of natural products, 81(4):1029-1035. Full article.
  • Nour Al-muhtasib, A. Sepulveda-Rodriguez, S. Vicini, and P. Forcelli. (2018). Neonatal phenobarbital exposure disrupts GABAergic synaptic maturation in rat CA1 neurons. Epilepsia,59(2):333-344. Full article.
  • Tuan EW, Horti AG, Olson TT, GAO Y, Stockmeier CA, Al-muhtasib N, Bowman Dalley C, Lewin AE, Wolfe BB, Sahibzada N, Xiao Y, Kellar KJ. (2015) AT-1001 is a partial agonist with high affinity and selectivity at human and rat alpha3beta4 nicotinic cholinergic receptors. Molecular pharmacology. 88(4):640-9. Full article.
  • Y. Zhou, W. Zhao, N. Al-muhtasib, GW. Rebeck. (2015) APOE genotype: alters immunoglobulin subtypes in knock-in mice. Journal of Alzheimer’s Disease. Full article.
  • Y. Liu, M. Paige, T. Olson, N. Al-muhtasib, T. Xie, S. Hou, M. White, A. Cordova, J. Guo, K. Kellar, Y. Xiao, M. Brown. (2014) Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A. Bioorganic & medicinal chemistry letters, 24(13):2954-6. Full article.
  • V. Yenogonda, Y. Xiao, E. Levin, A. Rezvani, T. Tran, N. Al-muhtasib, N. Sahibzada, T. Xie, C. Wells, S. Slade, J. Johnson, S. Dakshanamurthy, H. Kong, Y. Tomita, Y. Lieu, M. Paige, K. Kellar, M. Brown. (2013) Design, synthesis and discovery of picmolar selective alpha4beta2 nicotinic acetylcholine receptor ligands. Journal of Medicinal Chemistry, 52(21):8404-21. Full article.
  • Y. Liu, J. Richardson, T. Tran, N. Al-muhtasib, T. Xie, V. Yenugonda, H. Sexton, A. Rezvani, E. Levin, N. Sahibzada, K. Kellar, M. Brown, Y. Xiao, M. Paige. (2013) Chemistry and pharmacological studies of 3-alkoxy02,5-substituded-pyridyl compounds, novel selective alpha4beta2 nAChRs ligands that reduces alcohol Intake in Rats. Journal of Medicinal Chemistry, 56(7):3000-11. Full article.
  • C. Beinat, SD. Banister, S. van Prehn, D. MR. Doddareddy, D. Hibbs, M. Sako, M. Chebib, T. Tran, N. Al-muhtasib, Y. Xiao, M. Kassiou. (2012). Consequences of linker length alteration of the alpha7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333. Bioorganic & medicinal chemistry letters, 22(7):2380-4. Full article.

Teaching

  • 2017: Course instructor, Introduction to Neurophysiology
  • 2016-2017: Small group leader, Molecular and Cellular Physiology
  • 2016: Course director, Drugs, the Brain, and Behavior I
  • 2016: Course director, Drugs, the Brain, and Behavior II
  • 2015-2017: Course instructor, Drugs, the Brain, and Behavior I and II
  • 2013-2014: Course instructor, Principles of Pharmacology

Speaking

2018: Invited Panelist, Life After College Career Panel, University of Maryland, College Park

Awards and Honors

  • 2019: Ruth L. Kirschstein National Research Service Award (F32) Individual Postdoctoral Fellowship
  • 2017: Poster Award, American Physiological Society DMV Chapter Annual Meeting
  • 2017: Graduate Student Teaching Award, Georgetown University